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In neuronal cells, L-tryptophan could be converted to 5-HTP by TPH2 and then 5-HTP is converted to 5-HT by aromatic amino acid decarboxylase [29]

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Benoist 2014, PMID 25187433) were retracted in April 2025 (retraction notices PMID 40312092 and PMID 40312093) following a Washington State University investigation that found the lead author altered images across her dissertation and multiple co-authored papers