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Frontiers | Gut Metabolite Trimethylamine-N-Oxide in Atherosclerosis: From Mechanism to Therapy

News Release December 09, 2025 ConsumerLab’s Tests of Beetroot and Nitrate Products Yield Shocking Findings White Plains, NY, December 09, 2025 — Beetroot products are promoted for their naturally occurring nitrate, which can relax blood vessels and improve blood flow

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More recently, a family of potent and highly selective mechanism-based suicide substrate inhibitors were developed and shown to promote the irreversible inhibition of gut microbiota–dependent generation of TMA, suppression of host TMAO levels, and, in parallel, inhibition of platelet hyperresponsiveness and thrombosis potential in animal models (22)