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A promising priority lies in developing dual-target nanotherapeutics capable of concurrently suppressing ferroptosis drivers (e.g., ACSL4) and amplifying immunoregulatory pathways (e.g., Treg activation), thereby enabling synergistic correction of both redox and immune dysfunction

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Elderly subjects had fasting glucose 15% higher and insulin 469% higher, as well as insulin resistance 571% higher than in younger controls