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- Common methods for cell disruption include mechanical methods (such as bead milling or high-pressure homogenization) or enzymatic methods

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In response to the muscle damage and supplementation, circulating levels of free iron (that could possibly react to form hydroxyl radicals) were increased, lactate dehydrogenase and creatine kinase, markers of protein breakdown and damage, were elevated in the supplemented group as well as an increase in markers for oxidative stress