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Figure 1 L-carnitine, a TMA found abundantly in red meat, has aroused considerable research interest because an increasing number of studies have found that it is associated with atherosclerosis ( via intestinal flora-derived CntA/CntB , and also into γ-butyrobetaine and betaine, and further converted to TMA through the yeaW/yeaX enzyme system of intestinal flora (Figure 1