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Both peptides demonstrated strong ACE-inhibitory activity, with IC₅₀ values of 0.92 μmol/L for TTP and 3.4 μmol/L for gAgAP

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CagriSema vs Tirzepatide: Amylin/GLP-1 vs GIP/GLP-1 for Maximum Weight Loss Evidence-based comparison of CagriSema (amylin + GLP-1) and tirzepatide (GIP + GLP-1) for obesity, including REDEFINE and SURMOUNT trial data