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Silencing 5-HT 3A by short hairpin RNA slowed down tumor growth in an allograft CRC model, whereas treatment with the 5-HT 3A antagonist alleviated tumor progression in an azoxymethane/dextran sodium sulfate (AOM/DSS)-induced CRC mouse model [159]

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Rotenone is commonly used in solution as a pesticide, insecticide, or in emulsified liquid form as a piscicide [59,60]