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Possible B12 injection side effects tend to be mild and short-lived, and may include: Injection site pain, redness, or swelling Mild itching Brief diarrhea (less common) A feeling of warmth after the injection Serious side effects are rare

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“Some of our patients are found to be deficient in Vitamin B12, and through our physician prescribing appropriate vitamin supplementation, some individuals note an improvement in energy level,” she says